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Joseph D O'Connell Selected Research

BGC945

7/2013Development and binding mode assessment of N-[4-[2-propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-γ-glutamyl-D-glutamic acid (BGC 945), a novel thymidylate synthase inhibitor that targets tumor cells.

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Joseph D O'Connell Research Topics

Disease

1Lung Neoplasms (Lung Cancer)
07/2013
1Neoplasms (Cancer)
07/2013

Drug/Important Bio-Agent (IBA)

1raltitrexed (D 1694)IBA
07/2013
1BGC945IBA
07/2013
1Pharmaceutical PreparationsIBA
07/2013
1Folic Acid (Vitamin M)FDA LinkGeneric
07/2013
1Folic Acid AntagonistsIBA
07/2013
1Glycoproteins (Glycoprotein)IBA
07/2013
1LigandsIBA
07/2013
1Cell Surface ReceptorsIBA
07/2013
1Thymidylate SynthaseIBA
07/2013
1Glutamic Acid (Glutamate)FDA Link
07/2013